Medication
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Tiopronin (trade name Thiola) is a prescription thiol drug used to control the rate of Cystine precipitation and excretion in the disease Cystinuria.
Due to the rarity of the disorder, tiopronin falls under the classification of an orphan drug.
It is somewhat similar to penicillamine in both chemistry and pharmacology.In the U.S., the drug was marketed by Mission Pharmacal at $1.50 per pill, but the rights were bought by Retrophin, owned by Martin Shkreli, and the price increased to $30 per pill for a 100mg capsule.
Due to the rarity of the disorder, tiopronin falls under the classification of an orphan drug.
It is somewhat similar to penicillamine in both chemistry and pharmacology.In the U.S., the drug was marketed by Mission Pharmacal at $1.50 per pill, but the rights were bought by Retrophin, owned by Martin Shkreli, and the price increased to $30 per pill for a 100mg capsule.
D-Penicillamine, sold under the trade names of Cupripen, Cuprimine and others, is a medication primarily used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and lead poisoning. Penicillamine works by binding heavy metals such that they can be removed from the body in the urine. The wholesale cost in the developing world is about 0.55 to 1.20 USD a dose.
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